I want you to know something important: you don't have to spend every evening stressed about what's for dinner. When you make this creamy chicken penne once on a Sunday afternoon, you're setting yourself up for five days of real meals—no takeout, no scrambling. I've watched so many busy people in Saint Louis transform their weeks by dedicating just one cooking session to dishes like this. Pair it with simple sides like roasted carrots and potatoes, and you've built yourself an entire week of nourishing food. Let me show you how.
Prep Time 10 minutesminutes
Cook Time 25 minutesminutes
Total Time 35 minutesminutes
Servings 6
Calories 563kcal
Author Glennis Annis
Ingredients
For the Fresh Tomato Topping
4cupgrape tomatoes, halved lengthwisethese small tomatoes stay sweeter longer than beefsteak varieties
6tablespoonfresh basil leaves, torn by handnever chopped with a knife, which bruises the delicate herb
1tablespoonaged balsamic vinegaradds depth without overpowering the fresh tomatoes
2clovegarlic, minced very fineraw garlic flavor is sharp; use sparingly
Kosher salt and freshly ground black pepper to tasteadjust this as tomatoes vary in natural sweetness
2tablespoonextra virgin olive oilthe quality matters here since this is uncooked
For the Pasta Base
1pound4 ounces penne pasta, preferably bronze-cutthe rough texture holds sauce better than smooth pasta
2tablespoonkosher salt for pasta waterthis is your only seasoning opportunity for the pasta itself
For the Creamy Chicken and Sauce
2poundboneless skinless chicken breasts, cut into 1-inch piecesuniform sizing ensures even cooking
2cupchicken broth, preferably low-sodiumso you control the salt level
1teaspoonItalian seasoning blenddried oregano, basil, and thyme combined
3tablespoonall-purpose flourcreates the base for your sauce without lumps
3tablespoonunsalted butteradds richness without the salt of salted butter
10clovegarlic, mincedmore garlic than typical, because it mellows beautifully during cooking
½teaspooncrushed red pepper flakesadds subtle heat that builds through the week
½cupdry white wine or white cooking wineadds complexity; don't skip this
2cupfreshly grated Parmesan cheese, plus extra for servingfreshly grated melts more smoothly than pre-shredded varieties
2shallots, diced smallmilder and sweeter than onions in cream sauces
2cupheavy creamfull-fat cream prevents curdling during reheating throughout the week
Kosher salt and black pepper for seasoningapply generously to the chicken before cooking
Instructions
Step 1: Build Your Fresh Topping First
Start here because this step requires zero cooking and it needs time to sit. Combine your halved tomatoes, torn basil, olive oil, balsamic vinegar, minced garlic, salt, and pepper in a medium bowl. Stir gently and set it aside for at least 10 minutes while you handle the hot components. This resting time allows the tomato juices to release and all those flavors to marry together beautifully. Your topping will taste infinitely better than if you rushed it.
Step 2: Salt Your Pasta Water Generously
Fill a large pot three-quarters full with water and bring it to a rolling boil over high heat. Add 2 tablespoons of kosher salt—yes, that seems like a lot, but this is literally your only opportunity to season the pasta itself. The water should taste like the sea. This step takes about 12-15 minutes, so while you're waiting, prep your chicken pieces and shallots. Multitasking saves you serious time.
Step 3: Cook Your Pasta to Perfect Doneness
Once the water reaches a rolling boil, add all your penne and stir immediately to prevent sticking. Cook according to package directions, but taste it starting one minute before the package recommends. You want it al dente—tender but with just a slight firmness when you bite it. Overcooked pasta becomes mushy as it sits throughout the week. Drain it and set it aside in a large mixing bowl. Don't rinse it; the starch helps your sauce cling beautifully.
Step 4: Sear Your Chicken Until Golden
While your pasta cooks, heat 2 tablespoons of olive oil in a large, deep skillet over medium-high heat until it shimmers. Pat your chicken pieces dry with paper towels—this step is crucial for achieving that golden crust. Season generously with salt and pepper. Working in a single layer (don't crowd the pan), cook the chicken for 5-7 minutes, stirring occasionally, until the pieces are cooked through and golden on the outside.
You'll know it's done when there's no pink inside and a meat thermometer reads 165°F. Remove the chicken to a clean plate and set aside. Don't wash the skillet—those golden bits are liquid gold for your sauce.
Step 5: Create Your Cream Sauce Foundation
In the same skillet, melt 3 tablespoons of butter over medium heat. Add your diced shallots and cook for about 90 seconds, stirring occasionally, until they soften slightly and become fragrant. Add your 10 minced garlic cloves and cook for another 30 seconds—just enough to wake up those aromatics without letting them brown.
Sprinkle 3 tablespoons of flour over the mixture and stir constantly for 2 minutes. This creates a roux, the base that will thicken your cream sauce. You're not looking for browning here; you want a pale, paste-like consistency.
Step 6: Build Your Sauce Slowly
Here's where patience matters. Slowly pour in your 2 cups of chicken broth while whisking constantly to prevent lumps from forming. The continuous whisking breaks down any flour clumps and creates a silky sauce. Once the broth is fully incorporated and the sauce begins to thicken slightly (about 3-4 minutes), pour in your ½ cup of white wine.
Reduce the heat to low and simmer gently for 3-5 minutes while the sauce continues to thicken and the wine mellows. You're building layers of flavor here, not rushing to the finish line.
Step 7: Bring Back the Chicken and Add Cream
Return your cooked chicken to the skillet and stir gently to coat it with the sauce. Pour in your 2 cups of heavy cream, add 1 teaspoon of Italian seasoning and ½ teaspoon of crushed red pepper, and stir until everything is combined.
Bring the entire mixture to a gentle simmer over medium-low heat—you want tiny bubbles breaking the surface, not an aggressive boil. Let it simmer for 2-3 minutes so the flavors marry. Remove from heat and stir in your 2 cups of freshly grated Parmesan cheese until it's fully melted and incorporated.
Step 8: Combine Everything and Final Season
Pour your creamy chicken sauce over the cooked pasta in your large mixing bowl and stir gently until every piece of pasta is coated. Taste it and adjust your seasoning with salt and pepper as needed. The Parmesan adds saltiness, so go easy; you can always add more, but you can't take it out.
This is your complete base for the entire week. It should taste rich, creamy, and perfectly seasoned—like something you'd pay for at a nice restaurant.